Endometriosis as female reproductive system disorder: mechanisms, diagnosis and clinical management

Document Type : Review Paper

Authors

1 Member of Research Committee, Medical School, Hamedan University of Medical Sciences, Hamedan, Iran

2 Department of Anatomical Sciences, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran

10.22034/CAJMPSI.2021.04.03

Abstract

Endometriosis is a gynecological, chronic, and inflammatory disease affecting one in ten women globally. It occurs when tissues similar to the endometrial layer of the uterus grow outside the uterine body leading to inflammation, pain, and infertility. The most common site of endometriotic lesions is the pelvic cavity, especially the ovaries. Thus, at the same time as menstruation, these points initiate bleeding, which results in many difficulties. So far, several mechanisms of endometriosis have been suggested, such as retrograde menstruation, the influence of environmental and genetic factors, and hormonal causes. In some cases, this pathologic condition occurs following pregnancy or pelvic surgery. Disease management also involves the use of painkillers and contraceptive hormones for a relatively long time or even the use of laparoscopy to remove the pathologic lesions. In this review, the mechanisms of endometriosis were discussed, as well as various aspects of the disease in the field of diagnosis and treatment were assessed.

Graphical Abstract

Endometriosis as female reproductive system disorder: mechanisms, diagnosis and clinical management

Highlights

  • Endometriosis is a chronic and inflammatory gynecological disease that affects 10% of women.
  • Various factors such as environmental and genetic factors and hormonal factors can change the endometriosis risk.
  • Painkillers and contraceptive hormones can be good ways to treat the endometriosis.

Keywords

Main Subjects


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