Document Type : Case Report
Department of Oral and Maxillofacial Pathology, Oral and Maxillofacial Diseases Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Among odontogenic cysts, dentigerous cysts (DC) and among odontogenic tumors, ameloblastoma are the most common. Odontogenic tumors such as ameloblastoma can develop from the cyst lining of dentigerous cyst and also odontogenic keratocyst. DC is the most common form of odontogenic cyst, formed by the accumulation of fluid between the reduced enamel epithelium and the tooth crown, and is clinically associated with an unerupted tooth, most commonly an unerupted mandibular third molar, an upper canine, and a mandibular premolar.Radiographically, unilocular x-ray fluorescence with well-defined sclerotic margins surrounding the crown of an unerupted tooth is noted. Ameloblastoma is a neoplasm classified as a benign epithelial odontogenic tumor of the jaw. 70% of ameloblastomas develop in the molar-ramus region of the mandible and are occasionally associated with an unerupted third molar.Histologically, most ameloblastomas have a follicular or plexiform pattern, although basaloid, granular, or desmoplastic cellular changes may also occur. This study presents a case of aggressive plexiform mandibular ameloblastoma arising from the cyst lining of a dentigerous cyst in a 36-year-old male patient.
- Dentigerous cyst is the most common type of developmental odontogenic cysts.
- Ameloblastoma is the most common clinically significant odontogenic tumor.
- Ameloblastomas are tumors of odontogenic epithelial origin.
- Ameloblastomas can arise from the epithelial lining of odontogenic cyst.